Programming Cell Signaling Pathways with Engineered Protein Switches

Date and time: Friday, January 15, 2021 - 4:00 p.m. to 5:30 p.m.

Speaker: Xin Zhou, University of California-San Francisco

Synthetic protein switches, which detect a specific signal and convert it to a user-defined response, are invaluable tools in research and medicine. In this presentation, I will introduce the design and engineering of three versatile protein switches: light-responsive proteins, phosphotyrosine binders, and biosensors to detect SARS-CoV-2 antibodies. Excitingly, there are many diverse applications for these protein switches, ranging from studies investigating basic cell signaling biology to engineering the next generation of cancer immunotherapies. I will discuss the great potential of synthetic protein switches and propose future efforts to further push the boundaries of engineered biological responses. 

Zoom Link for Seminar:  https://princeton.zoom.us/j/97792813829

Meeting ID: 977 9281 3829    Passcode: 132676