Frontiers of health: Durable drugs

Fundamental approach targets practical problem Designing effective drugs and vaccines to combat and prevent disease is only half the battle—they also have to be formulated effectively for shipping and storage, which is where Pablo Debenedetti and Athanassios Panagiotopoulos come in. The chemical engineering professors use a combination of theoretical, computational and experimental techniques to explore how proteins behave in the presence of certain sugars that are often used as stabiliz

Frontiers of health: Developing understanding

The vials of fruit flies that line the shelves of Stas Shvartsman's lab would be expected in a biology lab, but Shvartsman is a chemical engineer. His approach to developmental biology -- as unconventional as his lab -- has promising implications for the prevention and treatment of birth defects and cancer.

Invest in education, people and the future, say Xerox and Amazon execs

A failure to invest in science and engineering education could have dire consequences in today's global economy, said corporate leaders from Xerox Corp. and in separate April addresses at Princeton.

Frontiers of health: Following the map

Mona Singh doesn't use the maps in her office to get from point A to point B -- she uses them to find meaning hidden in biological data, which may help advance the understanding of disease at the genetic level.

Smits returns as mechanical and aerospace chair

Alexander Smits will become chair of the Department of Mechanical and Aerospace Engineering as of July 1, returning to the position he held from 1998 to 2004.

Frontiers of health: Bugs for drugs

Bacteria have to work to earn their keep in the lab of David Wood, assistant professor of chemical engineering. Designed to respond to human hormones, the busy bugs may help identify new compounds to treat endocrine problems, including Graves' disease and estrogen-related disorders.

Frontiers of health: New spin on heart valves

In a roundabout way, propellers advanced Julie Young's latest project—a new and improved heart valve replacement. "The blades of a propeller look very much like the leaflets in a mechanical heart valve," said Young, an assistant professor of civil and environmental engineering, who studied propellers for her Ph.D. dissertation at the University of Texas at Austin. "The same principles apply on a much smaller scale."

Frontiers of health: Sight for sore eyes

Szymon Suckewer needs eye surgery, but he's not going under the knife just yet -- he'd rather wait until no knife is necessary. Having recently developed an incision-free eye surgery technique, he's confident that will soon be an option.

Frontiers of health: Killer proteins

Powerful proteins that are able to kill bacteria and viruses already exist in nature, but Kyle Vanderlick wants to make them even stronger. The chair of the chemical engineering department, Vanderlick conducts research on antimicrobial peptides -- short proteins that destroy disease-causing bugs by breaking down the membranes that surround them. The work, done in collaboration with biologists at the University of California, Irvine, could ultimately lead to the development of powerful new mic

Quest for ancient coins inspires a book and a course

Computer scientist Ken Steiglitz is happy to admit that he is an eBay addict. For starters, his pre-dawn "grazing" on the popular Internet trading site has yielded a trove of ancient bronze coins to add to his personal collection. Even more, he has discovered a wealth of information to advance the field of auction theory, which lies at the intersection of computer science, economics, mathematics and psychology.