Teaching and research in Operations Research and Financial Engineering (ORFE) focus on foundations of data science, probabilistic modeling, and optimal decision-making under uncertainty, with applications in economics and finance, energy and the environment, healthcare management, physical and biological sciences, social networks, and transportation. The graduate and undergraduate programs provide strong technical grounding in statistics, stochastics, and optimization, which are central in the analysis of massive datasets that arise in areas as diverse as the human genome and financial markets, and for applications ranging from clinical trials to robotics.